VECTASHIELD® Antifade Mounting Media
Antifade mounting media optimized for immunofluorescence applications
Choosing an effective mounting medium is especially important for immunofluorescence imaging. Fluorophores are susceptible to photobleaching and fading from both the imaging excitation light and during storage. The right mounting medium will protect your samples for short- and long-term use and archiving.
The VECTASHIELD, VECTASHIELD® PLUS, VECTASHIELD Vibrance®, and VECTASHIELD HardSet™ Antifade Mounting Media are well-established, market-leading products that complete the workflow and provide excellent signal retention for image acquisition and specimen archiving.

VECTASHIELD PLUS protects against fading across the visible spectrum, even under far-red wavelengths. It is compatible with most commercially available fluorophores. This new formulation of non-setting media improves upon the original VECTASHIELD products. Specifically, VECTASHIELD PLUS exhibits no inherent background or toning and provides superior fluorophore signal retention across the spectrum, including far-red wavelengths.
VECTASHIELD Vibrance is an aqueous mountant that sets at room temperature. Slides are viewable within one hour after mounting and can be stored at room temperature for extended periods, without loss of signal intensity, retraction of media or bubble formation. VECTASHIELD Vibrance Antifade Mounting Media provides excellent protection against fading across the visible spectrum, even under far-red wavelengths. It are compatible with most commercially available fluorophores
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Venn diagram showcasing the applications for which our various VECTASHIELD antifade mounting media are recommended.

Check out this video on coverslipping tips for Immunofluorescence slide mounting